Question

Which statement best describes the pathophysiologic changes associated with Guillain-Barré syndrome (GBS)?

A) Peripheral nerve demyelination and axonal degeneration
B) Central nervous system inflammation
C) Dopamine deficiency
D) Vascular occlusion and infarction

Answer 1

Guillain-Barré syndrome is characterized by peripheral nerve demyelination and axonal degeneration, leading to symptoms like tingling, weakness, and paralysis.

Step-by-step explanation:

Guillain-Barré syndrome is characterized by peripheral nerve demyelination and axonal degeneration. It is an autoimmune disease, often triggered by bacterial and viral infections, that leads to the destruction of myelin sheaths around neurons in the peripheral nervous system. This results in symptoms such as tingling, weakness, and paralysis.