Question

Which of the following statements regarding Glycopeptides (Vancomycin) is correct?

Option 1: Glycopeptides (Vancomycin) is effective against both gram-positive and gram-negative bacteria.

Option 2: Intravenous (IV) administration of Vancomycin is commonly used to treat bone, joint infections, and sepsis.

Option 3: Vancomycin is primarily used to treat infections caused by Methicillin-resistant Staphylococcus aureus (MRSA) and is effective against a wide range of bacteria.

Option 4: The toxicity associated with Vancomycin includes hepatotoxicity and gastrointestinal disturbances.

Answer 1

Vancomycin is primarily used to treat infections caused by MRSA and is effective against a wide range of bacteria.

Step-by-step explanation:

The correct statement regarding Glycopeptides (Vancomycin) is Option 3: Vancomycin is primarily used to treat infections caused by Methicillin-resistant Staphylococcus aureus (MRSA) and is effective against a wide range of bacteria.

Bacteriology literature states that Vancomycin is only effective against gram-positive organisms, which means it does not work against gram-negative bacteria (Options 1 and 2 are incorrect). It is commonly used for the treatment of MRSA infections and is also effective against other gram-positive bacteria (Option 3 is correct).

Additionally, Vancomycin has known toxicities, but not hepatotoxicity. It can cause nephrotoxicity, ototoxicity, and gastrointestinal disturbances like pseudomembranous colitis (Option 4 is incorrect).