Final answer:
The patient who would be at most risk for developing a venous thromboembolism (VTE) if a combination oral contraceptive was prescribed is the 22-year-old patient who smokes 2 packs of cigarettes per day.
Step-by-step explanation:
The patient who would be at most risk for developing a venous thromboembolism (VTE) if a combination oral contraceptive was prescribed is option C, the 22-year-old patient who smokes 2 packs of cigarettes per day. Smoking is a known risk factor for VTE, as it promotes inflammation and blood clotting. The use of birth control pills further increases the risk of VTE, especially in smokers.