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A primary health care provider has ordered frequent magnetic resonance imaging using a gadolinium contrast agent in a patient with kidney failure. The patient reports darkness of the skin, joint pain, and limited joint movement. What condition does the nurse suspect?

A. Asterixis
B. Hydronephrosis
C. Nephrogenic systemic fibrosis
D. Contrast-induced nephropathy

1 Answer

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Final answer:

The nurse suspects Nephrogenic Systemic Fibrosis (NSF) in a patient with kidney failure showing symptoms like skin darkening, joint pain, and limited joint mobility after receiving gadolinium contrast agent for MRI. NSF is associated with gadolinium exposure in patients with renal dysfunction and requires careful clinical evaluation for diagnosis.

Step-by-step explanation:

The condition that the nurse should suspect when a patient with kidney failure reports symptoms such as darkness of the skin, joint pain, and limited joint movement after frequent Magnetic Resonance Imaging (MRI) using gadolinium contrast agents is Nephrogenic Systemic Fibrosis (NSF). NSF is a rare but serious condition that affects patients with kidney dysfunction, particularly those with acute renal failure or chronic kidney disease (CKD). It is associated with the administration of gadolinium-based contrast agents which are used to enhance the quality of MRI scans.

For a patient with kidney dysfunction, MRI scans with gadolinium contrast should be used cautiously due to the risk of NSF, which may present with skin thickening, hyperpigmentation, and fibrosis of internal organs. When differential diagnosis is necessary, it is important to rule out other conditions such as Asterixis, Hydronephrosis, and Contrast-Induced Nephropathy, which may have different pathogeneses and courses of treatment. An accurate diagnosis of NSF in this context would require a comprehensive clinical evaluation, including assessing the patient's renal function history and exposure to gadolinium contrast agents.

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