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What specific type of P-type ATPase pumps H+ to acidify the stomach and is inhibited by proton pump inhibitor drugs used to treat excess stomach acid?

A) type 1
B) type 2
C) type 3
D) type 4
E) type 5

User Nweiler
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1 Answer

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Final answer:

The type of P-type ATPase that pumps H+ to acidify the stomach is Type 2: the hydrogen potassium ATPase or gastric proton pump. It is inhibited by proton pump inhibitors like omeprazole (Prilosec) and is essential for the function of the enzyme pepsin for protein digestion.

Step-by-step explanation:

The specific type of P-type ATPase that pumps H+ to acidify the stomach and is inhibited by proton pump inhibitor drugs is the hydrogen potassium ATPase, also known as the gastric proton pump or H+/K+ ATPase. This enzyme is crucial for the acidification of the stomach and is the target of proton pump inhibitors, which are a class of medication used to treat conditions like GERD, peptic ulcers, and Zollinger-Ellison syndrome. Such drugs include omeprazole (Prilosec) and are distinctly different from H₂-receptor antagonists like ranitidine (Zantac). The stomach's environment, due to the action of this ATPase, is highly acidic which is necessary for enzymes like pepsin to function effectively in protein digestion.To answer the student's multiple choice question: The type of P-type ATPase is Type 2.

User Pajics
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