Question

Sickle Cell disease:

Select one:
a. Results from a single base change
b. Causes hemoglobin to aggregate
c. Causes red blood cells to become sickle shaped
d. Blocks blood flow to organs
e. All of the above are correct

Answer 1

Sickle Cell disease involves a single base mutation in the beta-hemoglobin gene causing red blood cells to become sickle-shaped, leading to aggregation of hemoglobin, obstructed blood flow, and organ damage. All options a through d are correct, making e the correct answer.

Step-by-step explanation:

Sickle Cell disease encompasses multiple aspects: a. Results from a single base change in the gene for human beta-hemoglobin, b. Causes hemoglobin to aggregate forming long fibers that distort the shape of red blood cells, c. Causes red blood cells to become sickle shaped or crescent-like, and d. Blocks blood flow to organs because these misshapen cells can clog blood vessels and restrict oxygen delivery.

Therefore, the correct answer is e. All of the above are correct. Each aspect contributes to the overall impact of the disease which includes not only the sickling of red blood cells but also the complications resulting from this altered shape, like pain, swelling, and potential organ damage due to obstructed blood flow.