Question

_____ _____ causes the aggregation and activation of pro-apoptotic BH123 proteins (Bax and Bak).

a) DNA damage
b) Mitochondrial outer membrane permeabilization (MOMP)
c) Cell membrane rupture
d) Chromosome condensation

Answer 1

The aggregation and activation of pro-apoptotic BH123 proteins (Bax and Bak) are caused by mitochondrial outer membrane permeabilization (MOMP).

Step-by-step explanation:

The correct answer is option b) Mitochondrial outer membrane permeabilization (MOMP). Mitochondrial outer membrane permeabilization (MOMP) causes the aggregation and activation of pro-apoptotic BH123 proteins (Bax and Bak). MOMP refers to the permeabilization of the outer membrane of mitochondria, leading to the release of cytochrome C into the cytoplasm and the activation of apoptosis.