Final answer:
Gastric mucosal agents, such as misoprostol, are the prostaglandin drug classification used to treat GERD that inhibits gastric acid secretion and offers protective effects to the stomach lining from NSAIDs.
Step-by-step explanation:
The prostaglandin drug classification that is used to treat Gastroesophageal Reflux Disease (GERD) by inhibiting gastric acid secretion and protecting the stomach lining from irritating drugs such as NSAIDs is d. Gastric mucosal agents. These medications, like misoprostol, are analogs of prostaglandins which can decrease acid secretion and increase the production of protective mucus in the stomach lining, thereby preventing and treating the harmful effects of NSAIDs on the stomach.
While drugs like H₂-blockers and proton pump inhibitors also reduce stomach acid production, they are not classified under prostaglandins and do not provide protective effects against the damaging action of NSAIDs that gastric mucosal agents do. It's important to note that while all options listed can be related to managing symptoms associated with acid-related disorders, they belong to different drug classes and have varying mechanisms of action.