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What functional groups does CrO3 (jones oxidation with H2SO4 and acetone) oxidize

User Arjan Knol
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Final answer:

CrO3 (Jones oxidation with H2SO4 and acetone) can oxidize hydroxyl groups to aldehydes, carbonyl groups to carboxylic acids, and amines to aldehydes and amines.

Step-by-step explanation:

Jones oxidation with CrO3 and H2SO4/acetone is commonly used to oxidize primary and secondary alcohols. The functional groups that can be oxidized include:

Hydroxyl groups (OH) are oxidized to aldehydes or ketones.

Carbonyl groups (C=O) are oxidized to carboxylic acids.

Amines (NH2) are oxidized to aldehydes and amines (or ammonia for primary amines).

For example, primary alcohols can be oxidized to aldehydes:

R-CH2OH + CrO3 + H2SO4/acetone → R-CHO

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