Final answer:
The three factors around which aggravating factors revolve are biological, psychological, and social, as per the biopsychosocial model relevant to health and illness.
Step-by-step explanation:
The three factors that aggravating factors revolve around can be understood through the biopsychosocial model often used in health and illness contexts. This model suggests that there is an interplay between biological factors, psychological factors, and social factors that determine the overall health and wellness of an individual. When considering what may have contributed to John's illness, it's essential to examine any biological irregularities, such as genetic predispositions or current infections; psychological aspects, which include stress levels and mental health conditions; and social elements like personal relationships or community support systems. These aspects provide a comprehensive understanding of the contributing factors towards illness.