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What forces drive protein folding and which amino acid type are involved in each type of interaction?

User Tom Peplow
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Final answer:

Protein folding is driven by ionic bonding, hydrogen bonding, disulfide linkages, and dispersion forces. Amino acids with charged, polar, or hydrophobic R groups are involved in each type of interaction.

Step-by-step explanation:

Protein folding is driven by four major types of attractive interactions: ionic bonding, hydrogen bonding, disulfide linkages, and dispersion forces.

The types of amino acids involved in each type of interaction are:

  • Ionic bonding: Involves amino acids with charged R groups, such as lysine, arginine, and glutamate.
  • Hydrogen bonding: Involves amino acids with polar R groups, such as serine, threonine, and asparagine.
  • Disulfide linkages: Involves the amino acid cysteine, which can form covalent bonds with another cysteine residue.
  • Dispersion forces: Involves interactions between hydrophobic amino acids, such as leucine, isoleucine, and valine.

User Serhat MERCAN
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