135k views
4 votes
Which of the following would MOST LIKELY be considered part of a pharmacokinetics study?

A) Assessment of drug effects on the central nervous system

B) Evaluation of drug binding to its target receptor

C) Measurement of drug concentrations in blood over time

D) Investigation of drug metabolism in the liver

User Livea
by
7.9k points

1 Answer

2 votes

Final answer:

The scenario most likely representing a part of pharmacokinetics study is C) Measurement of drug concentrations in blood over time, as it aligns with the study of drug movement within the body and the determination of several key pharmacokinetic parameters.

Step-by-step explanation:

Pharmacokinetics is the branch of pharmacology concerned with the movement of drugs within the body, affected by the processes of absorption, distribution, metabolism, and excretion (ADME). Considering the options provided and the definitions of each term, measurement of drug concentrations in blood over time would MOST LIKELY be considered part of a pharmacokinetics study. This measure is a direct way to monitor and understand how drugs are processed within the body over time, which is a core aspect of pharmacokinetic studies.

During clinical development, it allows researchers to determine multiple pharmacokinetic parameters such as the maximum concentration (Cmax), the time to reach the Cmax (tmax), plasma drug concentration-time curve (AUC), and the elimination half-life (t1/2). Therefore, the correct answer is C) Measurement of drug concentrations in blood over time, as it aligns with the principle goals of pharmacokinetic analysis, which include the determination of drug absorption rate, bioavailability, and clearance, amidst others.

User Ebolton
by
8.5k points