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What is the role of vSNARE & tSNARE proteins?

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Final answer:

vSNARE and tSNARE proteins facilitate the fusion of vesicles with target membranes during intracellular transportation. V-SNARE proteins are located on transport vesicles and interact with complementary T-SNARE proteins on the target membrane, allowing fusion to occur.

Step-by-step explanation:

The role of vSNARE and tSNARE proteins is crucial in the process of vesicle transport within a cell. These SNARE proteins are involved in the docking and fusion of vesicles with their target membranes. vSNARE (vesicle-SNARE) proteins are incorporated into the membranes of transport vesicles during their formation, for example at the trans face of the Golgi apparatus. These vesicles carry specific cargo proteins to various destinations within the cell.

Upon reaching the target membrane, vSNARE proteins interact with tSNARE (target-SNARE) proteins found on the surface of the destination membrane, such as the plasma membrane or another organelle. This interaction is highly specific, ensuring that vesicles fuse only with the appropriate membranes. The binding between vSNARE and tSNARE facilitates the fusion of the vesicle membrane with the target membrane, allowing the transfer of the vesicle contents into the appropriate compartment or to the exterior of the cell in the case of secretion.

Other molecular players such as clathrin, GTPases like dynamin, and motor proteins like dynein and kinesin are also involved in vesicle trafficking. They assist in the formation, movement, and fusion of vesicles as part of the cell's endomembrane system. This complex process allows the cell to maintain proper function by directing proteins and other molecules to their correct locations.

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