Final answer:
Lipid-anchored proteins are found on either the cytoplasmic or extracellular side of the membrane, anchored by hydrophobic interactions or covalent attachments to membrane lipids, or non-covalent interactions with other membrane components.
Step-by-step explanation:
Lipid-anchored proteins are typically found on either side of the membrane. They can be located on the cytoplasmic side or the extracellular side of the plasma membrane. These proteins are anchored to the membrane by a hydrophobic domain that interacts non-covalently with the fatty acid interior, or they may be attached through interactions with the polar phosphate groups of phospholipids or with the polar domains of integral membrane proteins. Anchoring can also occur via covalent attachments to lipids within the membrane. Furthermore, peripheral proteins might bind to the membrane's surface through non-covalent interactions, such as hydrogen bonding and electrostatic forces with integral proteins and phospholipids.