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Is it true that the data obtained from the Meselson-Stahl experiment after one generation of replication eliminated the conservative model of DNA replication?

A) True
B) False

1 Answer

7 votes

Final answer:

The Meselson-Stahl experiment disproved the conservative model of DNA replication and confirmed the semi-conservative model after observing intermediate-density DNA bands after one replication generation.

Step-by-step explanation:

The data obtained from the Meselson-Stahl experiment after one generation of replication did indeed eliminate the conservative model of DNA replication, which makes the statement True. In the conservative model, the original DNA molecule was thought to be fully preserved while a completely new counterpart was synthesized. However, after one generation of growth in 14N medium, the single band of DNA observed had an intermediate density, which contradicted the conservative model and suggested a semi-conservative or dispersive model.

The Meselson-Stahl experiment ultimately supported the semi-conservative model of DNA replication, where each new DNA molecule consists of one parental strand and one newly synthesized strand. Additional replication rounds showing two bands, one at the intermediate density and the other at the 14N density, further confirmed semi-conservative replication.

User Ansel Santosa
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