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How can you identify an allele that has experienced recent strong positive selection?

a. By measuring the average heterozygosity (H) among marker loci.
b. By assessing the fraction of loci out of Hardy-Weinberg equilibrium (HWE).
c. By determining the fraction of marker-locus pairs in linkage disequilibrium (LD).
d. All of the above.

1 Answer

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Final answer:

To identify an allele that has experienced recent strong positive selection, measuring average heterozygosity, assessing the fraction of loci out of Hardy-Weinberg equilibrium, and determining the fraction of marker-locus pairs in linkage disequilibrium are all effective methods. Therefore, the correct answer is d. All of the above.

Explanation :

Linkage disequilibrium occurs when alleles at different loci are associated with each other more frequently than would be expected by chance. A high level of linkage disequilibrium may indicate that a selective sweep has occurred recently, where a beneficial allele has rapidly increased in frequency, bringing along nearby alleles.

Therefore, the correct answer is d. All of the above. By examining all these parameters, scientists can get a comprehensive view of evolutionary forces affecting allele frequencies, allowing them to infer that certain alleles have been subject to strong positive selection.

User Daniel Liuzzi
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