Question

The list of events below describes eukaryotic pre-mRNA processing. Please select the choice that lists the events in CORRECT sequential order.

1. Cleavage at the poly(A) site
2. Addition of the poly(A) tail
3. Addition of the 5′ cap
4. Export to the cytoplasm
5. The introns are removed
a) 3, 5, 1, 2, 4
b) 3, 1, 5, 2, 4
c) 5, 3, 1, 2, 4
d) 5, 1, 3, 2, 4

Answer 1

The correct sequence for eukaryotic pre-mRNA processing is 5' capping, intron removal, cleavage at the poly(A) site, addition of the poly(A) tail, and export to the cytoplasm, so the answer is a) 3, 5, 1, 2, 4.

Step-by-step explanation:

Your question concerns the correct sequential order of events in eukaryotic pre-mRNA processing. The processing of eukaryotic pre-mRNA includes several critical steps: 5' capping, intron removal, 3' cleavage, polyadenylation, and eventual export to the cytoplasm. Here is the accurate order of these events:

1. Addition of the 5′ cap
2. The introns are removed (splicing)
3. Cleavage at the poly(A) site
4. Addition of the poly(A) tail
5. Export to the cytoplasm

Following this order, the correct sequence from the choices you've provided would be: a) 3, 5, 1, 2, 4. This reflects 5' capping, intron splicing, cleavage at the poly(A) site, addition of the poly(A) tail, and finally the export of the mature mRNA to the cytoplasm.