Final answer:
Parkinson's disease targets dopaminergic cells in the substantia nigra, affecting dopamine levels and motor function control, with the correct answer being E) dopaminergic : substantia nigra.
Step-by-step explanation:
Parkinson's disease appears to target dopaminergic cells within the substantia nigra. Therefore, the correct answer is E) dopaminergic : substantia nigra. Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta, affecting the basal ganglia circuitry.
The death of these neurons leads to a reduction in dopamine levels, which is crucial for regulating motor function. The disease manifests through both motor symptoms like tremors and rigidity and non-motor symptoms including cognitive decline.