Final answer:
The sex-chromosome constitution of the inviable offspring from a cross between a white-eyed female (XwXwY) and a wild-type male in Drosophila melanogaster is XwXwY and YY.
Step-by-step explanation:
The sex-chromosome constitution of the inviable offspring resulting from a cross between a white-eyed female (XwXwY) and a wild-type male in Drosophila melanogaster would be (A) XwXwY and YY. The female fruit fly (XwXwY) has an abnormal chromosome composition, featuring two X chromosomes and one Y. This is typically lethal in Drosophila because it disrupts the balance of sex chromosomes, making the offspring inviable.
The white-eyed female can only pass on an Xw or the Y chromosome. A normal XY male will pass on either his X or Y chromosome. Therefore, potential inviable combinations would be XwXwY (having received an Xw from the mother and another Xw from the father, as well as the Y from the mother) or YY (having received Y chromosomes from both parents).