Final answer:
Tay-Sachs disease is a genetic disorder that results in the destruction of neurons due to a buildup of sphingolipids in the cells. The malfunctioning organelle in Tay-Sachs disease is the lysosome.
Step-by-step explanation:
Tay-Sachs disease is a genetic disorder that results in the destruction of neurons due to a buildup of sphingolipids in the cells. The malfunctioning organelle in Tay-Sachs disease is the lysosome. Lysosomes are responsible for breaking down various substances in the cell, but in Tay-Sachs, they cannot properly break down sphingolipids, leading to their accumulation and neuronal damage.