220k views
0 votes
Fragile X Syndrome
CGG repeats on the X-chr w/ anticipation.

1 Answer

5 votes

Final answer:

Fragile X Syndrome is associated with developmental delays and intellectual disability, often due to an increased number of CGG repeats on the X chromosome. Similar chromosomal disorders include triplo-X, Klinefelter syndrome, and Turner syndrome, which manifest various physical and developmental symptoms.

Step-by-step explanation:

Chromosomal Disorders and Fragile X Syndrome

Fragile X Syndrome is a genetic condition that arises due to the expansion of CGG nucleotide repeats on the X chromosome, showing a phenomenon known as anticipation. This disorder is related to developmental delays, intellectual disability, and physical features such as elongated face, large ears, and flexible joints. Cytologists have noted that errors such as duplications, deletions, inversions, and translocations in chromosomes can lead to various abnormalities and syndromes. For instance, triplo-X syndrome involves the presence of three X chromosomes leading to developmental delays and reduced fertility, while Klinefelter syndrome (XXY) results in males with physical changes including small testes and reduced body hair. Turner syndrome (XO) corresponds to females, often exhibiting short stature and sterility. Consequently, the symptom most associated with the disorder indicated by an altered number of X chromosomes, as in the case of Fragile X syndrome, would likely be developmental delays and intellectual challenges.

User Sirra Sneha
by
8.9k points