Final answer:
Dubin-Johnson Syndrome (DJS) is a liver disorder characterized by the accumulation of bilirubin in liver cells, causing a black liver discoloration. Rotor Syndrome (RS) does not cause this black liver discoloration. Both conditions may present with mild or no symptoms.
Step-by-step explanation:
Dubin-Johnson Syndrome (DJS) is a liver disorder characterized by the accumulation of a pigment called bilirubin in liver cells. This leads to a black or blackish-brown discoloration of the liver. However, Rotor Syndrome (RS) does not cause this black liver discoloration.
DJS is caused by a deficiency of a protein called MRP2, which is responsible for transporting bilirubin out of liver cells. On the other hand, RS is caused by a defect in the uptake of bilirubin by liver cells.
Both DJS and RS may present with mild or no symptoms. In some cases, there may be a pink or brown discoloration of the chin and increased sensitivity to sunlight in DJS.