Final answer:
The generation of radioactive waste, long-term environmental and health risks, and concerns of nuclear proliferation are key disadvantages of nuclear energy.
Step-by-step explanation:
The main disadvantage of nuclear energy compared to other alternative energy sources is the generation of radioactive waste. This waste includes materials like spent nuclear reactor fuel and uranium mill tailings, which can remain dangerous for thousands of years. The radioactive waste poses significant environmental and health risks, requiring secure and long-term storage solutions to prevent contamination. Moreover, there are concerns about nuclear proliferation and the potential for radioactive material to be diverted for destructive purposes. These factors along with the high cost of nuclear power plants are part of the complex debate surrounding the use of nuclear energy.