Final answer:
Diabetes mellitus is the most frequent cause of drug-induced nephrogenic diabetes insipidus (NDI), where the kidneys are unable to properly concentrate urine. Certain drugs, such as diuretics, can interfere with kidney function and lead to the development of this condition.
Step-by-step explanation:
Diabetes mellitus has become the most frequent cause of drug-induced nephrogenic diabetes insipidus (NDI). NDI is a condition where the kidneys are unable to properly concentrate urine, resulting in excessive urination and thirst. In the case of drug-induced NDI, certain drugs, such as diuretics, can interfere with kidney function and lead to the development of the condition.