Final answer:
The Consumer Product Safety Improvement Act of 2008 regulates phthalates and lead, both of which are chemicals with potential health risks.
Step-by-step explanation:
The two major chemicals regulated by the Consumer Product Safety Improvement Act of 2008 are phthalates and lead. Phthalates are synthetic chemicals that are used to soften plastics and are found in a multitude of consumer products, including cosmetics, toys, and food packaging. They are considered potential endocrine disruptors. Lead is a toxic heavy metal found in items such as paint, pipes, and toys, and it can accumulate in the body leading to serious health issues like cognitive impairments and behavioral problems.