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Explain why there may be a higher probability of cancer in epithelial tissue than in other tissues.

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Final answer:

Cancer is more likely to occur in epithelial tissue due to its high cell turnover and widespread presence throughout the body, both of which increase exposure to harmful agents and opportunities for mutations during cell division.

Step-by-step explanation:

The higher probability of cancer in epithelial tissue is primarily due to its characteristics and functions. Epithelial tissues are widespread throughout the body and are present in areas exposed to environmental factors that can lead to cell damage, such as the skin, airways, digestive tract, urinary and reproductive systems. These tissues are closely packed and form large sheets of cells that line both external and internal surfaces. Carcinoma refers to cancers that arise in epithelial cells, including those of the breast, prostate, lung, and colon. As epithelial cells have a high turnover rate, frequently dividing to replace damaged or dead cells, there is a greater chance for mutations to occur during DNA replication prior to cell division which can lead to cancerous growths. Moreover, the avascularity of epithelial tissues means that substances, including nutrients and potential carcinogens, must diffuse through these cells, potentially increasing exposure to harmful agents that can trigger carcinogenesis.

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