Final answer:
Web browser configurations can include homepage, privacy, security, add-ons, tabs, accessibility settings, and clearing browsing data. Microsoft has since transitioned to Edge, its newer browser, with updated features.
Step-by-step explanation:
Some configurations of a web browser application, such as Microsoft's Internet Explorer (IE), that can be adjusted include the homepage settings, privacy options like tracking protection and pop-up blocker settings, security settings including SmartScreen Filter, and the management of add-ons or plugins.
Additionally, users can configure tabs settings, accessibility options, and clear browsing history and cache. It's important to note that Microsoft transitioned from Internet Explorer to Microsoft Edge as their main browser, with continuous updates and changes in configurations and features.