Final answer:
Information system owners are responsible for operational issues regarding an agency's security controls, ensuring resource management, security measure implementation, and system effectiveness.
Step-by-step explanation:
Information system owners are responsible for any operational issues associated with the implementation of an agency's common security controls. The role of the system owner involves ensuring that all aspects of the system operation are managed in accordance with the agency’s security policies and procedures. This includes managing resources, overseeing the implementation of proper security measures, and ensuring that the system operates effectively and that security controls are properly maintained.