Question

A sample of cancer cells from a breast cancer tumor were treated with various concentrations of a drug, drug X. The percent survival for these tumor cells is shown in the graph here. Which statements are supported by the experimental design and the data shown in the graph? Select ALL that apply. A * B 4x D The safest dose of the drug is 1000 micromolar concentration. C All concentrations of the drug show a decrease in cell survival compared to the control. E The cells survive but stop dividing at low concentration of the drug. Only concentrations above 100 micromolar for drug X allow for greater than 50% of the cells to die. The dose response curve indicates that higher concentrations of the drug are more effective at decreasing cell viability of the cancer cells.​

Answer 1

The experimental design and data in the graph support statements regarding the safest dose, decrease in cell survival, concentration threshold for cell death, and the effectiveness of higher drug concentrations in decreasing cell viability.

Step-by-step explanation:

The experimental design and the data shown in the graph support the following statements:

• The safest dose of the drug is 1000 micromolar concentration. This is because at this concentration, the percent survival of the cancer cells is the highest (around 90%).
• All concentrations of the drug show a decrease in cell survival compared to the control. This is evident from the fact that the percent survival decreases as the drug concentration increases.
• Only concentrations above 100 micromolar for drug X allow for greater than 50% of the cells to die. This is supported by the graph, where only concentrations above 100 micromolar show a decrease in survival to less than 50%.
• The dose-response curve indicates that higher concentrations of the drug are more effective at decreasing cell viability of the cancer cells. This is evident from the downward trend of the curve, indicating that as the drug concentration increases, the cell viability decreases.