Final answer:
To address malicious PDF attachments in emails, you should implement Microsoft Defender for Office 365, which provides real-time protection and capabilities to remove threats from inboxes and disable malicious content.
Step-by-step explanation:
The feature you should implement to remove a malicious email with a PDF attachment from inboxes and disable the PDF threat if an affected document is opened is a) Microsoft Defender for Office 365. This security solution provides protection in real-time against threats in email messages, links (URLs) and collaboration tools. It covers various types of threats including phishing, malicious software, or malware hidden in email attachments like the mentioned PDF.
Microsoft Defender for Office 365 includes threat investigation and response capabilities, which allow administrators to search for and delete malicious emails from users' inboxes after they've been delivered. Additionally, it includes features that can recognize and block potentially harmful attachments or scripts as they're being accessed, thus providing an extra layer of security against threats posed by files that may seem benign at first glance.