Question

A 36-year-old man with a history of recurrent epigastric pain undergoes an upper GI endoscopy, which reveals a well-demarcated shallow ulcer of the gastric antrum. Histologic examination of a biopsy specimen shows evidence of angiogenesis, granulation tissue, fibrosis, and infiltrating lymphocytes, macrophages, and plasma cells. The most appropriate term to describe this pathologic process is:

Option 1: Chronic gastritis.
Option 2: Peptic ulcer disease.
Option 3: Acute gastritis.
Option 4: Gastric carcinoma.

Answer 1

The appropriate term to describe the pathologic process is peptic ulcer disease. It is a sore that develops in the lining of the stomach or duodenum, often associated with Helicobacter pylori. The histologic examination shows characteristic features of a peptic ulcer.

Step-by-step explanation:

The most appropriate term to describe the provided pathologic process is peptic ulcer disease. A peptic ulcer is a sore that develops in the lining of the stomach or duodenum, often associated with the bacterium Helicobacter pylori. It is typically diagnosed through symptoms or the presence of H. pylori in the GI tract, and can be visualized through endoscopy.

The histologic examination of the biopsy specimen in this case reveals evidence of angiogenesis, granulation tissue, fibrosis, and infiltrating lymphocytes, macrophages, and plasma cells, which are characteristic of peptic ulcers.

The presence of recurrent epigastric pain and a well-demarcated shallow ulcer of the gastric antrum further supports the diagnosis of peptic ulcer disease.