Final answer:
The orbitofrontal cortex is believed to play a critical role in Obsessive-Compulsive Disorder (OCD), contributing to the difficulty in inhibiting intrusive thoughts and repetitive behaviors.
Step-by-step explanation:
The brain region believed to play a critical role in Obsessive-Compulsive Disorder (OCD) is the orbitofrontal cortex. This region is part of the prefrontal cortex, which is responsible for executive functions and goal-directed behaviors.
OCD is characterized by intrusive thoughts and repetitive behaviors. Dysfunction in the orbitofrontal cortex may contribute to the difficulty in inhibiting these thoughts and actions, leading to the symptoms of OCD.
Research studies have shown hyperactivation of the orbitofrontal cortex in individuals with OCD during symptom provocation tasks, further supporting its involvement in the disorder.