Final answer:
The major phagocytic cells in acute inflammation are neutrophils, macrophages, and dendritic cells. Neutrophils act as initial responders, while macrophages and dendritic cells play roles in the ongoing phagocytic process and in linking immune responses.
Step-by-step explanation:
The major phagocytic cells that are involved in the process of acute inflammation include neutrophils, macrophages, and to a lesser extent, dendritic cells. Neutrophils are often the first responders to a site of infection or injury, constituting 50-60 percent of all leukocytes. They are known for their ability to engulf and digest pathogens using intracellular lysosomes. They follow neutrophils and take over the phagocytosis function, cleaning up cell debris and pathogens.
Following the neutrophils, macrophages arrive to continue the process of phagocytosis by cleaning up cell debris and pathogens, playing a crucial role in resolving inflammation. Dendritic cells also participate by engulfing pathogens and are pivotal in linking the innate and adaptive immune responses.