Final answer:
Fluoxetine (Prozac®) is the least preferred medication for the treatment of depression in an 82-year-old man. Other medications like Sertraline (Zoloft®), Citalopram (Celexa®), and Escitalopram (Lexapro®) may be safer alternatives.
Step-by-step explanation:
In the treatment of depression in an 82-year-old man, the least preferred medication option from the given list would be Fluoxetine (Prozac®).
Fluoxetine is an SSRI, or selective serotonin reuptake inhibitor, that works by increasing the levels of serotonin in the central nervous system. While SSRIs are commonly used to treat depression, fluoxetine specifically may not be the best choice for elderly patients due to its long half-life, which can increase the risk of drug interactions and side effects.
Other medications like Sertraline (Zoloft®), Citalopram (Celexa®), and Escitalopram (Lexapro®) may be safer alternatives for treating depression in an 82-year-old man.