Final answer:
The most likely diagnosis for the presented symptoms is an Early intrauterine pregnancy, considering the Beta-hCG levels, absence of adnexal masses, and the presence of a fluid collection in the uterus. Other serious conditions are less likely based on the information provided.
Step-by-step explanation:
The most likely diagnosis for a 28-year-old G0 woman presenting with a two-day history of spotting, left lower quadrant pain, no history of sexually transmitted infections, and being a smoker is C.
Early intrauterine pregnancy. The presence of spotting could indicate implantation bleeding, and the mild tenderness on pelvic exam could be due to changes occurring in early pregnancy.
The Beta-hCG level is appropriate for a very early pregnancy, and the ultrasound findings of a fluid collection in the uterus without adnexal masses or free fluid can suggest an early gestational sac or implantation fluid. The other options such as ovarian torsion, missed abortion, and ectopic pregnancy are less likely given the clinical and ultrasound findings, and more information would be needed to establish one of those diagnoses with confidence.