Final answer:
An endonuclease is the enzyme involved in nucleotide excision repair, responsible for excising damaged DNA strands, which is then replaced with correctly paired nucleotides by DNA polymerase and sealed by DNA ligase.
Step-by-step explanation:
The enzyme involved in nucleotide excision repair (NER) is an endonuclease. During NER, enzymes, such as the UvrABC endonuclease complex in bacteria, recognize and excise damaged DNA stretches affecting longer strands of 2-30 bases. This includes bulky, helix-distorting changes like thymine dimers as well as single-strand breaks. The process involves making cuts on both the 3' and 5' ends of the damaged base. After removal of the incorrect sequence, DNA polymerase (DNA pol) fills in the gap with correctly paired nucleotides followed by DNA ligase sealing the gap with a phosphodiester linkage.
The enzyme involved in nucleotide excision repair is an endonuclease. Nucleotide excision repair is a process that recognizes and repairs bulky, helix-distorting changes in DNA, such as thymine dimers or single-strand breaks. In this repair mechanism, an endonuclease enzyme makes cuts on both the 3' and 5' ends of the damaged base, allowing for the removal and replacement of the segment with correctly paired nucleotides.