Final answer:
The body synthesizes uric acid to maintain normal blood concentrations and must match the excretion rate, which ranges from 250 to 750 mg per day. Elevated uric acid levels can cause conditions like gout, and treatment often involves diet modifications and drugs like allopurinol.
Step-by-step explanation:
The daily synthetic rate of uric acid in humans is not directly specified in the available data, but we can infer it from the normal concentration and excretion rates. The normal concentration of uric acid in the blood is 2.4 to 7.0 mg/dl, and it is excreted in the urine at the rate of 250 to 750 mg per day. Therefore, the body must synthesize a comparable amount to maintain these levels, factoring in dietary intake and purine metabolism.
Excessive levels of uric acid can lead to conditions such as gout and kidney stones. Uric acid crystals form in the joints, causing painful inflammation. To manage or prevent gout, foods high in purines, such as certain meats, should be limited, and medical intervention with drugs like allopurinol which inhibits xanthine oxidase is common to lower blood uric acid levels.
Notably, different conditions that result in increased nucleic acid turnover, such as trauma, disease, or high-protein diets, can lead to elevated levels of uric acid in the blood, emphasizing the need for a balanced diet and proper functionality of the renal system for uric acid clearance.