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Loss-of-function alleles are often inherited in a dominant manner
a. true
b. false

1 Answer

3 votes

Final answer:

Loss-of-function alleles can be inherited in dominant or recessive manners. However, they are more commonly inherited in a recessive manner. Therefore, the statement that loss-of-function alleles are often inherited in a dominant manner is false. Option number b is followed.

Step-by-step explanation:

Lethal alleles can be inherited in two different manners: dominant or recessive. Loss-of-function alleles, which are alleles that result in nonfunctional proteins, can be inherited in both dominant and recessive manners, depending on their specific characteristics. However, in general, loss-of-function alleles are more commonly inherited in a recessive manner, rather than dominant.

A dominant inheritance pattern means that individuals with one copy of the dominant allele will display the phenotype associated with that allele. In the case of dominant lethal alleles, individuals with one copy of the allele will still experience the lethal effect. This means that individuals who inherit the dominant lethal allele will not survive, whether they are in the homozygous or heterozygous state. Thus, the statement that loss-of-function alleles are often inherited in a dominant manner is false.

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