Question

All of the proteins below should be retained by the ER instead of going to the Golgi EXCEPT?

1) SRP receptor
2) SRP
3) Translocation channel
4) Signal peptidase
5) Hormone receptor

Answer 1

The proteins retained by the ER instead of going to the Golgi are the SRP receptor, SRP, and translocation channel. These proteins are involved in the process of protein translocation.

Step-by-step explanation:

The proteins that should be retained by the ER instead of going to the Golgi are the ones involved in the process of protein translocation. These include the SRP receptor, SRP (signal recognition particle), and the translocation channel. The SRP receptor is responsible for binding to the SRP-ribosome complex and guiding it to the ER membrane.

The SRP helps to recognize the hydrophobic signal peptide and bind to it, halting translation until the complex reaches the ER. The translocation channel then facilitates the movement of the growing polypeptide chain into the ER lumen. On the other hand, the signal peptidase catalyzes the hydrolysis of the signal peptide, allowing it to remain embedded in the ER membrane. Finally, hormone receptors are not involved in the process of protein translocation and would not be retained by the ER.