Question

Over what range of mean arterial pressure does glomerular filtration rate remain stable due to intrinsic regulation?

1) 50-150 mm Hg
2) 80-180 mm Hg
3) 70-110 mm Hg
4) 80-100 mm Hg
5) 80-120 mm Hg

Answer 1

The glomerular filtration rate remains stable due to intrinsic regulation over a mean arterial pressure range of 70-110 mm Hg.

Step-by-step explanation:

The stability of the glomerular filtration rate (GFR) is maintained through a mechanism known as renal autoregulation. This autoregulatory mechanism ensures that the GFR remains relatively stable over a certain range of mean arterial pressures. According to the information provided, as long as the mean arterial pressure is above approximately 60 mm Hg, the pressure will be adequate to maintain glomerular filtration. Normally, the mean arterial pressure (MAP) falls within the range of 70-110 mm Hg. This is the range where the GFR is maintained despite fluctuations in systemic blood pressure. Therefore, the correct answer to the question, 'Over what range of mean arterial pressure does glomerular filtration rate remain stable due to intrinsic regulation?' is 70-110 mm Hg.