Question

What might explain the condition of a person who appears female but has an XY chromosome pair?

1) Androgen Insensitivity Syndrome
2) Turner Syndrome
3) Klinefelter Syndrome
4) Down Syndrome

Answer 1

Individuals who appear female but have an XY chromosome pair may have Androgen Insensitivity Syndrome (AIS), which is a condition where the body is unable to respond to male sex hormones. This results in the development of external female genitalia and secondary sexual characteristics.Option 1 is the correct answer.

Step-by-step explanation:

Individuals who appear female but have an XY chromosome pair may be explained by the condition known as Androgen Insensitivity Syndrome (AIS). In AIS, there is a genetic mutation that makes the body unable to respond to male sex hormones (androgens). As a result, individuals with AIS develop external female genitalia and secondary sexual characteristics, even though they have XY chromosomes.

Androgen Insensitivity Syndrome (AIS) elucidates the phenomenon of individuals appearing female despite possessing an XY chromosome pair. This condition arises from a genetic mutation that impairs the body's responsiveness to male sex hormones, specifically androgens. In AIS, the normal cellular reception of androgens is disrupted, leading to an inability to manifest male secondary sexual characteristics.

Consequently, individuals with AIS develop external female genitalia and exhibit the physical traits associated with femininity, despite the underlying XY chromosomal composition. This condition underscores the intricate interplay between genetic factors and hormone signaling in the determination of sexual development and emphasizes the complexity of sex determination beyond chromosomal configurations.