Question

Viral genomes _________.

1) can be made of DNA.
2) can be made of RNA.
3) can be either double-stranded or single-stranded.

Answer 1

Viral genomes can be composed of DNA or RNA and can be either double-stranded or single-stranded. Positive single-strand RNA viruses can directly serve as mRNA, while negative single-strand RNA viruses need to convert to positive strands before protein synthesis.

Step-by-step explanation:

Viral genomes demonstrate a remarkable range of variation in terms of their structure and composition. Viruses may contain genomes that are composed of DNA or RNA. This means that the viral genome can either be double-stranded DNA (dsDNA), resembling cellular genomes, or single-stranded DNA (ssDNA), which then typically requires a conversion to dsDNA for subsequent processes like transcription. Additionally, viral genomes can be made of double-stranded RNA (dsRNA) or single-stranded RNA (ssRNA).

It is important to note that positive single-strand RNA viruses (+ssRNA) have genomes that can directly serve as mRNA for protein synthesis upon infection of a host cell. Conversely, negative single-strand RNA viruses (-ssRNA) require the synthesis of a complementary +ssRNA by an RNA-dependent RNA polymerase (RdRP) before protein synthesis can occur. This diversity in viral genome structures has significant implications for their replication and the overall viral life cycle.