Final answer:
The inner and outer nuclear membranes are continuous but maintain distinct protein compositions. The outer nuclear membrane is not studded with ribosomes. The endoplasmic reticulum lumen is not continuous with the nuclear interior.
Step-by-step explanation:
The correct answer is TFFF. Let's go through each statement:
T - The inner and outer nuclear membranes are continuous with each other, but they maintain distinct protein compositions.
F - The outer nuclear membrane is not studded with ribosomes engaged in protein synthesis. Ribosomes are bound to the rough endoplasmic reticulum (RER).
F - The endoplasmic reticulum lumen is not continuous with the nuclear interior. The lumen of the RER is continuous with the space separating the nuclear envelope membranes.
F - Ribosomal proteins pass through the nuclear pore complexes only once. They are imported into the nucleus after synthesis, where they combine with ribosomal RNA to form ribosomal subunits. These subunits are then exported from the nucleus.
Therefore, the correct answer is TFFF.