Question

What are some evidence of death of a cell within a tissue or organ by necrosis?

1) Cell shrinkage
2) Cell swelling
3) Disruption of cell membrane
4) Release of cellular contents
5) All of the above

Answer 1

Necrosis is indicated by cell swelling, disruption of the cell membrane, and the release of cellular contents. Cell shrinkage is typically associated with apoptosis, not necrosis.The correct answers are option 2),3) and 4)

Step-by-step explanation:

Evidence of the death of a cell within a tissue or organ by necrosis includes several features, such as cell swelling, disruption of the cell membrane, and the release of cellular contents. Unlike apoptosis, which is a form of programmed cell death and involves cell shrinkage and the formation of apoptotic bodies, necrosis is characterized by the loss of membrane integrity and cell lysis, which leads to inflammation in the surrounding tissue. Therefore, the correct option that includes evidence of necrosis is:

2) Cell swelling
3) Disruption of cell membrane
4) Release of cellular contents

It should be noted that cell shrinkage is typically associated with apoptosis and not necrosis. Additionally, unlike necrotic cells, apoptotic cells do not release their contents in a manner that causes harm to neighboring cells. In necrosis, once the membrane is compromised, cell components, including enzymes and other damaging substances, leak out into the surrounding area, potentially causing further damage to adjacent cells and tissues.