Question

A nurse is evaluating a client who is receiving amphotericin IV via intermittent IV bolus. Which of the following findings indicates an adverse reaction to this medication?

a) Decreased heart rate
b) Increased respiratory rate
c) Hypertension
d) Elevated temperature

Answer 1

Amphotericin, an antifungal medication, is known to cause adverse reactions, with fever being a common side effect. The correct answer is d) Elevated temperature.

Step-by-step explanation:

The elevation in temperature is often a sign of an infusion-related reaction, specifically termed "infusion-related fever." This fever is believed to result from the release of cytokines and other immune mediators triggered by the amphotericin. Therefore, the nurse should closely monitor the client's temperature during the infusion.

It's crucial to recognize that the other options (a) Decreased heart rate, (b) Increased respiratory rate, and (c) Hypertension are not typically associated with amphotericin administration. Instead, these findings might indicate other issues or reactions.

For instance, a decreased heart rate may suggest a bradycardic response unrelated to the medication, while an increased respiratory rate could signal respiratory distress. Hypertension, on the other hand, is not a commonly reported side effect of amphotericin. Therefore, the nurse should prioritize addressing the elevated temperature as a potential adverse reaction to the medication. Regular monitoring and prompt intervention are essential in managing these reactions and ensuring the client's safety during the course of treatment.

The correct answer is d) Elevated temperature.