Final answer:
Nat Turner led a slave rebellion in 1831, known as Nat Turner's Rebellion, in Southampton County, Virginia, which was the largest and deadliest slave uprising in U.S. history.
Step-by-step explanation:
The individual who led a group of enslaved African Americans in rebellion against their slaveholders in 1831 was Nat Turner. This event, known as Nat Turner's Rebellion, occurred in Southampton County, Virginia. Turner, deeply influenced by the evangelical fervor of the Second Great Awakening and his own religious visions, used Biblical passages to inspire and rally more than seventy followers to his cause.
The rebellion launched in late August of 1831 resulted in the death of around sixty white individuals before it was suppressed by a local militia. The insurrection led to severe consequences for many involved, with fifty-five slaves tried and executed. In the aftermath, the rebellion had a significant impact on the South's approach to slavery, including harsher laws against slave education and freedom of assembly.