Final answer:
Curley's wife's reaction with Lennie parallels Lennie's encounter with Crooks in that both interactions underscore a sense of isolation experienced by the characters in 'Of Mice and Men'.
Step-by-step explanation:
The question asks how Curley's wife's reaction with Lennie parallels Lennie's first encounter with Crooks from the novella 'Of Mice and Men' by John Steinbeck. The correct answer is C. Both encounters result in a sense of isolation. In both interactions, Lennie experiences a sense of being different and not fully accepted, although the dynamics of each encounter are unique. Curley's wife's reaction and the interaction with Crooks both highlight different aspects of loneliness and isolation experienced by characters in the story.