Final answer:
The Monroe Doctrine was a response to the interest of European nations in creating colonies in the Americas. It aimed to assert the United States' dominance in the Western Hemisphere and prevent European colonization.
Step-by-step explanation:
The Monroe Doctrine was largely a response to the interest of European nations in creating colonies in North and South America.
In 1823, President James Monroe issued the Monroe Doctrine which stated that the United States would guarantee the independence of nations in the Western Hemisphere and warned European nations to refrain from interfering with independent countries in the region.
The doctrine was a way for the United States to assert its dominance in the Americas and prevent European colonization, aligning with the view that American and European political systems were different and neither side should meddle in the affairs of the other.