Question

You are examining population association data to map factors associated with testicular cancer. Here are some of the genotypes and associated phenotypes. Which of these markers is likely closest to a factor causing testicular cancer?AA healthy:

1228, diseased: 217Aa healthy: 434, diseased: 76aa healthy: 38, diseased:
7BB healthy: 1115, diseased: 10Bb healthy: 560, diseased: 190bb healthy:
25, diseased: 100CC healthy: 1143, diseased: 202Cc healthy: 502, diseased:
88cc healthy: 55, diseased: 10DD healthy: 612, diseased: 108Dd healthy:
816, diseased: 144dd healthy: 272, diseased: 48

Answer 1

The marker closest to a factor causing testicular cancer is the bb genotype.

Step-by-step explanation:

The marker closest to a factor causing testicular cancer can be determined by looking at the genotypes and phenotypes of the different markers. In this case, the genotypes and phenotypes given are:

AA healthy: 1228, diseased: 217

Aa healthy: 434, diseased: 76

aa healthy: 38, diseased: 7

BB healthy: 1115, diseased: 10

Bb healthy: 560, diseased: 190

bb healthy: 25, diseased: 100

CC healthy: 1143, diseased: 202

Cc healthy: 502, diseased: 88

cc healthy: 55, diseased: 10

DD healthy: 612, diseased: 108

Dd healthy: 816, diseased: 144

dd healthy: 272, diseased: 48

From these data, we can see that the marker with the most significant difference between healthy and diseased individuals is the bb genotype. In the healthy group, there are 25 individuals with the bb genotype, while in the diseased group, there are 100 individuals with the bb genotype. This suggests that the bb genotype may be closest to a factor causing testicular cancer.