Final answer:
The possible genotypes in the F1 generation would be heterozygous red-eyed females (XWXw) and white-eyed males (XWY). The ratio of genotype and phenotype in the F1 generation would be 1:1.
Step-by-step explanation:
In this cross, a white-eyed male fruit fly is crossed with a heterozygous red-eyed female fruit fly. The Punnett square is used to determine the possible genotypes and eye colors of the offspring. The Punnett square would show that there is a 50% chance of producing red-eyed females and a 50% chance of producing white-eyed males in the F1 generation. Therefore, the possible genotypes and eye colors in the F1 generation would be:
1. Heterozygous red-eyed females (XWXw)
2. White-eyed males (XWY)
The ratio of genotype in the F1 generation would be 1:1, meaning equal numbers of heterozygous red-eyed females and white-eyed males. The ratio of phenotype would also be 1:1 since the red-eyed phenotype is dominant over the white-eyed phenotype.